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Lower pre-conditioning absolute lymphocyte counts are associated with worse outcomes in haploidentical stem cell transplantation with myeloablative regimen in children

BackgroundAnti-thymocyte globulin (ATG) is frequently administered for preventing graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT). In patients with low absolute lymphocyte count (ALC) before conditioning, weight-based dosing of ATG may cause overexp...

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Principais autores: Kai Cui, Senlin Zhang, Yueke Du, Yutan Chai, Mingchu Liang, Shaoyan Hu, Jie Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-03-01
coleção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1552263/full
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