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Lower pre-conditioning absolute lymphocyte counts are associated with worse outcomes in haploidentical stem cell transplantation with myeloablative regimen in children

BackgroundAnti-thymocyte globulin (ATG) is frequently administered for preventing graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT). In patients with low absolute lymphocyte count (ALC) before conditioning, weight-based dosing of ATG may cause overexp...

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Hlavní autoři: Kai Cui, Senlin Zhang, Yueke Du, Yutan Chai, Mingchu Liang, Shaoyan Hu, Jie Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-03-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1552263/full
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