Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids

ABSTRACT Nasal colonization by Staphylococcus aureus or Streptococcus pneumoniae is associated with an increased risk of infection by these pathobionts, whereas nasal colonization by Dolosigranulum species is associated with health. Human nasal epithelial organoids (HNOs) differentiated at air-liqui...

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Autores principales:	Andrea I. Boyd, Leah A. Kafer, Isabel F. Escapa, Amal Kambal, Hira Tariq, Susan G. Hilsenbeck, Hoa Nguyen-Phuc, Anubama Rajan, Joshua M. Lensmire, Kathryn A. Patras, Pedro A. Piedra, Sarah E. Blutt, Katherine P. Lemon
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2025-10-01
Colección:	mSphere
Materias:	human nasal organoids HNO nasal colonization epithelial innate immune response bacterial colonization Dolosigranulum pigrum
Acceso en línea:	https://journals.asm.org/doi/10.1128/msphere.00493-25
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