Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis.

<h4>Background</h4>Hepatic dysfunction and jaundice are traditionally viewed as late features of sepsis and portend poor outcomes. We hypothesized that changes in liver function occur early in the onset of sepsis, yet pass undetected by standard laboratory tests.<h4>Methods and findings</h4>In a lon...

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Bibliografiske detaljer

Principais autores:	Peter Recknagel, Falk A Gonnert, Martin Westermann, Sandro Lambeck, Amelie Lupp, Alain Rudiger, Alex Dyson, Jane E Carré, Andreas Kortgen, Christoph Krafft, Jürgen Popp, Christoph Sponholz, Valentin Fuhrmann, Ingrid Hilger, Ralf A Claus, Niels C Riedemann, Reinhard Wetzker, Mervyn Singer, Michael Trauner, Michael Bauer
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2012-01-01
Serier:	PLoS Medicine
Online adgang:	https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001338&type=printable
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