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Population pharmacokinetic modeling of multiple-dose intravenous fosfomycin in critically ill patients during continuous venovenous hemodialysis

Abstract The aim of this study was to investigate the pharmacokinetics of multiple-dose intravenous (i.v.) fosfomycin in critically ill patients during continuous venovenous hemodialysis (CVVHD). Non-compartmental analysis and population pharmacokinetic modeling were used to simulate different dosin...

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Principais autores: Tobias Hüppe, Katharina M. Götz, Andreas Meiser, Andrea de Faria Fernandes, Felix Maurer, Heinrich V. Groesdonk, Thomas Volk, Thorsten Lehr, Sascha Kreuer
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2023-10-01
Serija:Scientific Reports
Online dostop:https://doi.org/10.1038/s41598-023-45084-5
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