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Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans

Neuronal cell fate determinants establish the identities of neurons by controlling gene expression to regulate neuronal morphology and synaptic connectivity. However, it is not understood if neuronal cell fate determinants have postmitotic functions in synapse pattern formation. Here we identify a n...

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Principais autores: Mizuki Kurashina, Jane Wang, Jeffrey Lin, Kathy Kyungeun Lee, Arpun Johal, Kota Mizumoto
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
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Acceso en liña:https://elifesciences.org/articles/66011
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