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Bifidobacterium adolescentis induces Decorin+ macrophages via TLR2 to suppress colorectal carcinogenesis

Abstract Background The interplay between gut microbiota and tumor microenvironment (TME) in the pathogenesis of colorectal cancer (CRC) is largely unknown. Here, we elucidated the functional role of B. adolescentis and its possible mechanism on the manipulation of Decorin+ macrophages in colorectal...

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Autori principali: Yifeng Lin, Lina Fan, Yadong Qi, Chaochao Xu, Dingjiacheng Jia, Yao Jiang, Shujie Chen, Liangjing Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2023-07-01
Serie:Journal of Experimental & Clinical Cancer Research
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Accesso online:https://doi.org/10.1186/s13046-023-02746-6
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