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Bifidobacterium adolescentis induces Decorin+ macrophages via TLR2 to suppress colorectal carcinogenesis

Abstract Background The interplay between gut microbiota and tumor microenvironment (TME) in the pathogenesis of colorectal cancer (CRC) is largely unknown. Here, we elucidated the functional role of B. adolescentis and its possible mechanism on the manipulation of Decorin+ macrophages in colorectal...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yifeng Lin, Lina Fan, Yadong Qi, Chaochao Xu, Dingjiacheng Jia, Yao Jiang, Shujie Chen, Liangjing Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-07-01
Schriftenreihe:Journal of Experimental & Clinical Cancer Research
Schlagworte:
Colorectal cancer
B.adolescentis
Macrophages
Decorin
TLR2
Online-Zugang:https://doi.org/10.1186/s13046-023-02746-6
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