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Nonmonotonic Pathway Gene Expression Analysis Reveals Oncogenic Role of p27/Kip1 at Intermediate Dose

The mechanistic basis by which the level of p27 Kip1 expression influences tumor aggressiveness and patient mortality remains unclear. To elucidate the competing tumor-suppressing and oncogenic effects of p27 Kip1 on gene expression in tumors, we analyzed the transcriptomes of squamous cell papillom...

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Bibliografische Detailangaben
Hauptverfasser: Hien H Nguyen, Susan C Tilton, Christopher J Kemp, Mingzhou Song
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2017-11-01
Schriftenreihe:Cancer Informatics
Online-Zugang:https://doi.org/10.1177/1176935117740132
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