USP35, regulated by estrogen and AKT, promotes breast tumorigenesis by stabilizing and enhancing transcriptional activity of estrogen receptor α
Abstract Although endocrine therapies targeting estrogen receptor α (ERα) are effective in managing ER positive (+) breast cancer, many patients have primary resistance or develop resistance to endocrine therapies. In addition, ER+ breast cancer with PIK3CA activating mutations and 11q13-14 amplific...
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| Główni autorzy: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2021-06-01
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| Seria: | Cell Death and Disease |
| Dostęp online: | https://doi.org/10.1038/s41419-021-03904-4 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
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