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Targeting NLRP3 Inflammasome With Nrf2 Inducers in Central Nervous System Disorders

The NLRP3 inflammasome is an intracellular multiprotein complex that plays an essential role in the innate immune system by identifying and eliminating a plethora of endogenous and exogenous threats to the host. Upon activation of the NLRP3 complex, pro-inflammatory cytokines are processed and relea...

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Hlavní autoři: Bora Tastan, Burak I. Arioz, Sermin Genc
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-03-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.865772/full
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