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Novel Cross-Cancer Hub Genes in Doxorubicin Resistance Identified by Transcriptional Mapping

<b>Background:</b> Doxorubicin (DOX) is a widely used chemotherapeutic agent, but its efficacy is often limited by cancer cell resistance. Although multiple DOX resistance mechanisms have been characterized, the global transcriptomic alterations underlying this phenomenon remain poorly understood. T...

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Main Authors: Arseny D. Moralev, Oleg V. Markov, Marina A. Zenkova, Andrey V. Markov
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-10-01
Series:Biomedicines
Subjects:
chemoresistance
MDR
doxorubicin
cancer
hub gene
regulome
Online Access:https://www.mdpi.com/2227-9059/13/10/2527
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