Revealing Clonal Responses of Tumor-Reactive T-Cells Through T Cell Receptor Repertoire Analysis

CD8+ T cells are the key effector cells that contribute to the antitumor immune response. They comprise various T-cell clones with diverse antigen-specific T-cell receptors (TCRs). Thus, elucidating the overall antitumor responses of diverse T-cell clones is an emerging challenge in tumor immunology...

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Bibliografski detalji

Glavni autori:	Hiroyasu Aoki, Shigeyuki Shichino, Kouji Matsushima, Satoshi Ueha
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-01-01
Serija:	Frontiers in Immunology
Teme:	CD8+ T cell T-cell receptor repertoire single-cell TCR-seq immune check inhibitors cancer-immunity cycle inter-organ clone tracking
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.807696/full
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