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Revealing Clonal Responses of Tumor-Reactive T-Cells Through T Cell Receptor Repertoire Analysis

CD8+ T cells are the key effector cells that contribute to the antitumor immune response. They comprise various T-cell clones with diverse antigen-specific T-cell receptors (TCRs). Thus, elucidating the overall antitumor responses of diverse T-cell clones is an emerging challenge in tumor immunology...

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Principais autores: Hiroyasu Aoki, Shigeyuki Shichino, Kouji Matsushima, Satoshi Ueha
格式: Artigo
语言:Inglês
出版: Frontiers Media S.A. 2022-01-01
丛编:Frontiers in Immunology
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在线阅读:https://www.frontiersin.org/articles/10.3389/fimmu.2022.807696/full
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