mTORC1 Mediates Biphasic Mechano‐Response to Orchestrate Adhesion‐Dependent Cell Growth and Anoikis Resistance

Abstract Cells constantly sense and respond to not only biochemical but also biomechanical changes in their microenvironment, demanding for dynamic metabolic adaptation. ECM stiffening is a hallmark of cancer aggressiveness, while survival under substrate detachment also associates with poor prognos...

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Detalhes bibliográficos

Principais autores:	Chunlei Zhang, Yuan Wang, Zifeng Zhen, Jiayi Li, Jing Su, Congying Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-02-01
coleção:	Advanced Science
Assuntos:	autophagy cell adhesion mechano‐transduction mTORC1
Acesso em linha:	https://doi.org/10.1002/advs.202307206
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