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mTORC1 Mediates Biphasic Mechano‐Response to Orchestrate Adhesion‐Dependent Cell Growth and Anoikis Resistance

Abstract Cells constantly sense and respond to not only biochemical but also biomechanical changes in their microenvironment, demanding for dynamic metabolic adaptation. ECM stiffening is a hallmark of cancer aggressiveness, while survival under substrate detachment also associates with poor prognos...

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書誌詳細
主要な著者: Chunlei Zhang, Yuan Wang, Zifeng Zhen, Jiayi Li, Jing Su, Congying Wu
フォーマット: Artigo
言語:Inglês
出版事項: Wiley 2024-02-01
シリーズ:Advanced Science
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オンライン・アクセス:https://doi.org/10.1002/advs.202307206
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