Whole genome sequencing identifies novel mutations in malaria parasites resistant to artesunate (ATN) and to ATN + mefloquine combination

IntroductionThe global evolution of resistance to Artemisinin-based Combination Therapies (ACTs) by malaria parasites, will severely undermine our ability to control this devastating disease.MethodsHere, we have used whole genome sequencing to characterize the genetic variation in the experimentally...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Gustavo Capatti Cassiano, Axel Martinelli, Melina Mottin, Bruno Junior Neves, Carolina Horta Andrade, Pedro Eduardo Ferreira, Pedro Cravo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-03-01
Serie:	Frontiers in Cellular and Infection Microbiology
Soggetti:	plasmodium drug resistance artemisinin combination treatment genomics molecular dynamics simulations
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcimb.2024.1353057/full
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!