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Detoxication Strategy of Epoxide Hydrolase—The Basis for a Novel Threshold for Definable Genotoxic Carcinogens

From our recent work on the three-dimensional structure of epoxide hydrolases we theoretically deduced the likelihood of a two-step catalytic mechanism that we and others have subsequently experimentally confirmed. Analysis of the rate of the two steps by us and by others show that the first step—re...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Franz Oesch, Jan Georg Hengstler, Michael Arand
Hōputu: Artigo
Reo:Inglês
I whakaputaina: SAGE Publishing 2004-01-01
Rangatū:Dose-Response
Urunga tuihono:https://doi.org/10.1080/15401420490426963
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