Heat shock protein 22 alleviates doxorubicin-induced kidney injury by suppressing oxidative stress and apoptosis

Abstract This study investigated the effects of heat shock protein 22 (HSP22) against doxorubicin (DOX)-induced kidney injury. Mice were randomly assigned to four groups: CON, ad-HSP22, DOX, and ad-HSP22 + DOX. Adeno-associated virus carrying the HSP22 gene (ad-HSP22) was administered via tail vein...

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Autors principals:	Yuan-feng Zhou, Yang Fu, Ze-qun Lai, Hai-ling Xu, Na Shen, Jun Long, Huang Zhang, Yi-fei Dong
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-10-01
Col·lecció:	Scientific Reports
Matèries:	HSP22 DOX Kidney injury Oxidative stress Apoptosis
Accés en línia:	https://doi.org/10.1038/s41598-024-75277-5
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