Heat shock protein 22 alleviates doxorubicin-induced kidney injury by suppressing oxidative stress and apoptosis

Abstract This study investigated the effects of heat shock protein 22 (HSP22) against doxorubicin (DOX)-induced kidney injury. Mice were randomly assigned to four groups: CON, ad-HSP22, DOX, and ad-HSP22 + DOX. Adeno-associated virus carrying the HSP22 gene (ad-HSP22) was administered via tail vein...

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Detalhes bibliográficos

Principais autores:	Yuan-feng Zhou, Yang Fu, Ze-qun Lai, Hai-ling Xu, Na Shen, Jun Long, Huang Zhang, Yi-fei Dong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-10-01
Colecção:	Scientific Reports
Assuntos:	HSP22 DOX Kidney injury Oxidative stress Apoptosis
Acesso em linha:	https://doi.org/10.1038/s41598-024-75277-5
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