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Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III.

Multiple relationships between ubiquitin-proteasome mediated protein turnover and transcriptional activation have been well documented, but the underlying mechanisms are still poorly understood. One way to induce degradation is via ubiquitination of the N-terminal α-amino group of proteins. The majo...

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Autori principali: Yves B Beaulieu, Jorge A Leon Machado, Sylvain Ethier, Luc Gaudreau, Viktor Steimle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4752451?pdf=render
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