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Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomization

Introduction: Metabolic syndrome (MetS) increases the risk of cardiovascular disease and death. Previous ‘-omics’ studies have identified dysregulated serum metabolites and aberrant DNA methylation in the setting of MetS. However, the relationship between the metabolome and epigenome have not been e...

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Principais autores: Alana C. Jones, Zsuzsanna Ament, Amit Patki, Ninad S. Chaudhary, Vinodh Srinivasasainagendra, Naruchorn Kijpaisalratana, Devin M. Absher, Hemant K. Tiwari, Donna K. Arnett, W. Taylor Kimberly, Marguerite R. Irvin
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2023-09-01
Serija:Frontiers in Genetics
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Online dostop:https://www.frontiersin.org/articles/10.3389/fgene.2023.1184661/full
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