Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface

Summary: The arginine deiminase (ADI) pathway has been found in many kinds of bacteria and functions to supplement energy production and provide protection against acid stress. The Streptococcus pyogenes ADI pathway is upregulated upon exposure to various environmental stresses, including glucose st...

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Autori principali:	Yujiro Hirose, Masaya Yamaguchi, Tomoko Sumitomo, Masanobu Nakata, Tomoki Hanada, Daisuke Okuzaki, Daisuke Motooka, Yasushi Mori, Hiroshi Kawasaki, Alison Coady, Satoshi Uchiyama, Masanobu Hiraoka, Raymond H. Zurich, Masayuki Amagai, Victor Nizet, Shigetada Kawabata
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2021-03-01
Serie:	Cell Reports
Soggetti:	Streptococcus pyogenes arginine arginine deiminase pathway bacterial viability bacterial pathogenesis glucose starvation
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124721002382
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