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Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface

Summary: The arginine deiminase (ADI) pathway has been found in many kinds of bacteria and functions to supplement energy production and provide protection against acid stress. The Streptococcus pyogenes ADI pathway is upregulated upon exposure to various environmental stresses, including glucose st...

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Principais autores: Yujiro Hirose, Masaya Yamaguchi, Tomoko Sumitomo, Masanobu Nakata, Tomoki Hanada, Daisuke Okuzaki, Daisuke Motooka, Yasushi Mori, Hiroshi Kawasaki, Alison Coady, Satoshi Uchiyama, Masanobu Hiraoka, Raymond H. Zurich, Masayuki Amagai, Victor Nizet, Shigetada Kawabata
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-03-01
coleção:Cell Reports
Assuntos:
Streptococcus pyogenes
arginine
arginine deiminase pathway
bacterial viability
bacterial pathogenesis
glucose starvation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124721002382
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