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Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability stress

The transgenerational effects of exposing male mice to chronic social instability (CSI) stress are associated with decreased sperm levels of multiple members of the miR-34/449 family that persist after their mating through preimplantation embryo (PIE) development. Here we demonstrate the importance...

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Principais autores: Alexandre Champroux, Yang Tang, David A. Dickson, Alice Meng, Anne Harrington, Lucy Liaw, Matteo Marzi, Francesco Nicassio, Thorsten M. Schlaeger, Larry A. Feig
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2024-12-01
Series:Epigenetics
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Acceso en liña:https://www.tandfonline.com/doi/10.1080/15592294.2024.2346694
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