Ginger (Zingiber officinale) phytochemicals—gingerenone-A and shogaol inhibit SaHPPK: molecular docking, molecular dynamics simulations and in vitro approaches

Abstract Background Antibiotic resistance is a defense mechanism, harbored by pathogens to survive under unfavorable conditions. Among several antibiotic resistant microbial consortium, Staphylococcus aureus is one of the most havoc microorganisms. Staphylococcus aureus encodes a unique enzyme 6-hyd...

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Hlavní autoři:	Shailima Rampogu, Ayoung Baek, Rajesh Goud Gajula, Amir Zeb, Rohit S. Bavi, Raj Kumar, Yongseong Kim, Yong Jung Kwon, Keun Woo Lee
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2018-04-01
Edice:	Annals of Clinical Microbiology and Antimicrobials
Témata:	Ginger phytochemicals 6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase GOLD Shogaol Gingerenone-A MD simulations
On-line přístup:	http://link.springer.com/article/10.1186/s12941-018-0266-9
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