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Placental sex-dependent spermine synthesis regulates trophoblast gene expression through acetyl-coA metabolism and histone acetylation

Sex-dependent metabolism of spermine alter trophoblast gene expression through acetyl-coA biosynthesis and histone acetylation, indicating that escape of spermine synthase from X-linked inactivation partially contributes to placental sex differences.

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Bibliografiset tiedot
Päätekijät: Irving L. M. H. Aye, Sungsam Gong, Giulia Avellino, Roberta Barbagallo, Francesca Gaccioli, Benjamin J. Jenkins, Albert Koulman, Andrew J. Murray, D. Stephen Charnock-Jones, Gordon C. S. Smith
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2022-06-01
Sarja:Communications Biology
Linkit:https://doi.org/10.1038/s42003-022-03530-6
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