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Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1)

Niemann-Pick type C (NPC) protein functions to move unesterified cholesterol from the lysosomal compartment to other intracellular sites for further metabolism and/or excretion. This cholesterol is brought into the cell through the coated-pit pathway and accumulates in the lysosomes when NPC protein...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chonglun Xie, Stephen D. Turley, John M. Dietschy
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2000-08-01
Rangatū:Journal of Lipid Research
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S0022227520334362
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