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Molecular mechanisms of the Guizhi decoction on osteoarthritis based on an integrated network pharmacology and RNA sequencing approach with experimental validation

Background: Our aim was to determine the potential pharmacological mechanisms of the Guizhi decoction (GZD) in the treatment of osteoarthritis (OA) through an integrated approach of network pharmacological analyses, RNA sequencing (RNA-seq), and experimental validation.Methods: The quality control a...

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Bibliografiske detaljer
Principais autores: Yan Chen, Yan Xue, Xuezong Wang, Ding Jiang, Qinguang Xu, Lin Wang, Yuxin Zheng, Ying Shi, Yuelong Cao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-01-01
Serier:Frontiers in Genetics
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2023.1079631/full
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