Molecular mechanisms of the Guizhi decoction on osteoarthritis based on an integrated network pharmacology and RNA sequencing approach with experimental validation

Background: Our aim was to determine the potential pharmacological mechanisms of the Guizhi decoction (GZD) in the treatment of osteoarthritis (OA) through an integrated approach of network pharmacological analyses, RNA sequencing (RNA-seq), and experimental validation.Methods: The quality control a...

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Bibliografische Detailangaben

Hauptverfasser:	Yan Chen, Yan Xue, Xuezong Wang, Ding Jiang, Qinguang Xu, Lin Wang, Yuxin Zheng, Ying Shi, Yuelong Cao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-01-01
Schriftenreihe:	Frontiers in Genetics
Schlagworte:	Guizhi decoction osteoarthritis network pharmacology RNA sequencing TNF signaling pathway
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1079631/full
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