Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival

HDGF-related protein 2 (HRP-2) is a member of the Hepatoma-Derived Growth Factor-related protein family that harbors the structured PWWP and Integrase Binding Domain, known to associate with methylated histone tails or cellular and viral proteins, respectively. Interestingly, HRP-2 is a paralog of L...

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Detalhes bibliográficos

Principais autores:	Siska Van Belle, Sara El Ashkar, Kateřina Čermáková, Filip Matthijssens, Steven Goossens, Alessandro Canella, Courtney H. Hodges, Frauke Christ, Jan De Rijck, Pieter Van Vlierberghe, Václav Veverka, Zeger Debyser
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-01-01
Colecção:	Cells
Assuntos:	leukemia molecular cell biology protein complex protein-protein interaction nuclear magnetic resonance (NMR) animal model
Acesso em linha:	https://www.mdpi.com/2073-4409/10/1/192
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