APP‐C31: An Intracellular Promoter of Both Metal‐Free and Metal‐Bound Amyloid‐β40 Aggregation and Toxicity in Alzheimer's Disease

Abstract Intracellular C‐terminal cleavage of the amyloid precursor protein (APP) is elevated in the brains of Alzheimer's disease (AD) patients and produces a peptide labeled APP‐C31 that is suspected to be involved in the pathology of AD. But details about the role of APP‐C31 in the development of...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Eunju Nam, Yuxi Lin, Jiyong Park, Hyunsu Do, Jiyeon Han, Bohyeon Jeong, Subin Park, Da Yong Lee, Mingeun Kim, Jinju Han, Mu‐Hyun Baik, Young‐Ho Lee, Mi Hee Lim
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2024-01-01
Цуврал:	Advanced Science
Нөхцлүүд:	accelerator toward amyloidogenesis amyloid precursor protein amyloid‐β metal ions protein–protein interaction
Онлайн хандалт:	https://doi.org/10.1002/advs.202307182
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!