Method development for detection of E545A mutation PIK3CA gene in breast cancer patients using Tm Shift SYBR Green I qPCR
E545A is one of the point mutations, and its frequency is high in PIK3CA gene (3.8%), particularly breast cancer patients in Singapore (13.8%) and Mexico (11.5%). In addition to induce breast cancer, the mutation also caused resistance of anti-HER2 in HER2 cancer subtype. The tremendous effect of th...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Universitas Gadjah Mada, Yogyakarta
2016-06-01
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| Series: | Indonesian Journal of Biotechnology |
| Assuntos: | |
| Acceso en liña: | https://jurnal.ugm.ac.id/ijbiotech/article/view/26815 |
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