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PIK3CA mutations in endocrine-resistant breast cancer

Abstract Around 75% of breast cancer (BC) patients have tumors expressing the predictive biomarker estrogen receptor α (ER) and are offered endocrine therapy. One-third eventually develop endocrine resistance, a majority with retained ER expression. Mutations in the phosphatidylinositol bisphosphate...

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Autori principali: Caroline Schagerholm, Stephanie Robertson, Hosein Toosi, Emmanouil G. Sifakis, Johan Hartman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-05-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-024-62664-1
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