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Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis.

Langerhans cell histiocytosis (LCH) is a rare disease caused by the clonal accumulation of dendritic Langerhans cells, which is often accompanied by osteolytic lesions. It has been reported that osteoclast-like cells play a major role in the pathogenic bone destruction seen in patients with LCH and...

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Hlavní autoři: Frédéric Grosjean, Sonia Nasi, Pascal Schneider, Véronique Chobaz, Alexandra Liu, Vanessa Mordasini, Kristell Moullec, Paolo Vezzoni, Christine Lavanchy, Nathalie Busso, Hans Acha-Orbea, Driss Ehirchiou
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2015-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4527720?pdf=render
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