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E3 Ubiquitin Ligase Smurf1 Regulates the Inflammatory Response in Macrophages and Attenuates Hepatic Damage during Betacoronavirus Infection

The E3 ubiquitin ligase Smurf1 catalyzes the ubiquitination and proteasomal degradation of several protein substrates related to inflammatory responses and antiviral signaling. This study investigated the role of Smurf1 in modulating inflammation induced by Betacoronavirus infection. Bone marrow-der...

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Tallennettuna:
Päätekijät: Luiz P. Souza-Costa, Felipe R. S. Santos, Jordane C. Pimenta, Celso M. Queiroz-Junior, Fernanda L. Tana, Danielle C. Teixeira, Manoela G. G. Couto, Natalia F. M. Oliveira, Rafaela D. Pereira, Vinicius A. Beltrami, Pedro A. C. Costa, Larisse S. B. Lacerda, Josiane T. Andrade-Chaves, Pedro P. G. Guimarães, Renato S. Aguiar, Mauro M. Teixeira, Vivian V. Costa, Luis H. Franco
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2024-10-01
Sarja:Pathogens
Aiheet:
Smurf1
Betacoronavirus
MHV-A59
inflammation
macrophages
Linkit:https://www.mdpi.com/2076-0817/13/10/871
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