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Understanding Fc function for rational vaccine design against pathogens

ABSTRACTAntibodies represent the primary correlate of immunity following most clinically approved vaccines. However, their mechanisms of action vary from pathogen to pathogen, ranging from neutralization, to opsonophagocytosis, to cytotoxicity. Antibody functions are regulated both by antigen specif...

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Bibliografiske detaljer
Principais autores: Kathryn A. Bowman, Paulina Kaplonek, Ryan P. McNamara
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2024-01-01
Serier:mBio
Fag:
Online adgang:https://journals.asm.org/doi/10.1128/mbio.03036-23
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