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Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity

ABSTRACT Despite the robust immunogenicity of SARS-CoV-2 mRNA vaccines, emerging data have revealed enhanced neutralizing antibody and T cell cross-reactivity among individuals that previously experienced COVID-19, pointing to a hybrid immune advantage with infection-associated immune priming. Beyon...

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Principais autores: Kathryn A. Bowman, Daniel Stein, Sally Shin, Kathie G. Ferbas, Nicole H. Tobin, Colin Mann, Stephanie Fischinger, Erica Ollmann Saphire, Douglas Lauffenburger, Anne W. Rimoin, Grace Aldrovandi, Galit Alter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2022-10-01
Serier:mBio
Fag:
COVID-19
Fc-receptors
hybrid immunity
SARS-CoV-2
antibody function
vaccines
Online adgang:https://journals.asm.org/doi/10.1128/mbio.01647-22
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