TonEBP as a key regulator of hypothalamic leptin signaling and resistance

Abstract Tonicity-responsive enhancer binding protein (TonEBP) is a transcription factor implicated in cellular stress and inflammation. Here, we explore the role of TonEBP as a key regulator of leptin signaling and resistance. Using TonEBP haploinsufficient [TonEBP (+/-)] mice, we demonstrated that...

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Autors principals:	Han Rae Kim, Dasol Kang, Dong Hee Kim, Bora Jeong, Kwangkon Kim, Byong Seo Park, Hye Rim Yang, Hyug Moo Kwon, Marco Koch, Colin N. Young, Byung Ju Lee, Jae Geun Kim
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2026-03-01
Col·lecció:	Cellular and Molecular Life Sciences
Matèries:	TonEBP SOCS3 Hypothalamus Energy metabolism Leptin resistance
Accés en línia:	https://doi.org/10.1007/s00018-026-06150-z
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