Ponatinib confers adult human cardiomyocyte toxicity via inhibition of AKT signaling
Abstract As a widely used anticancer drug for the treatment of chronic myeloid leukemia, ponatinib is known to cause severe cardiovascular toxicities. Cardiomyocytes are the major functional units in the myocardium, and impairment of their viability and function plays a crucial role in cardiotoxic r...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Wiley
2026-04-01
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| Serija: | Physiological Reports |
| Teme: | |
| Online dostop: | https://doi.org/10.14814/phy2.70877 |
| Oznake: |
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