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ZDHHC13 prevents cuproptosis and enhances radioresistance in nasopharyngeal carcinoma cells by modulating FDX1 protein palmitoylation

Abstract Background Radioresistance is a major obstacle in antitumor therapies. This study explores the effects and functional mechanisms of zDHHC palmitoyltransferase 13 (ZDHHC13) on radioresistance in nasopharyngeal carcinoma (NPC). Methods Bioinformatic and tumor tissue microarray analyses were p...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Xianjun Lin, Xinrong Hu, Shenhong Qu, Xiaoxue Wang, Haiyun Zhao, Lingping Kong, Jinzhong Huang, Li Zhang, Qing Wen, Xi Lei, Pan Zou
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-04-01
Rangatū:European Journal of Medical Research
Ngā marau:
Nasopharyngeal carcinoma
Radioresistance
ZDHHC13
Cuproptosis
FDX1
Palmitoylation
Urunga tuihono:https://doi.org/10.1186/s40001-026-04336-6
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