IgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, Fc-glycans and a fab-Peptide sequence.

The Fc-glycan profile of IgG1 anti-citrullinated peptide antibodies (ACPA) in rheumatoid arthritis (RA) patients has recently been reported to be different from non-ACPA IgG1, a phenomenon which likely plays a role in RA pathogenesis. Herein we investigate the Fc-glycosylation pattern of all ACPA-Ig...

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Principais autores:	Susanna L Lundström, Cátia Fernandes-Cerqueira, A Jimmy Ytterberg, Elena Ossipova, Aase H Hensvold, Per-Johan Jakobsson, Vivianne Malmström, Anca I Catrina, Lars Klareskog, Karin Lundberg, Roman A Zubarev
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2014-01-01
coleção:	PLoS ONE
Acesso em linha:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113924&type=printable
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