SNM1A is crucial for efficient repair of complex DNA breaks in human cells

Abstract DNA double-strand breaks (DSBs), such as those produced by radiation and radiomimetics, are amongst the most toxic forms of cellular damage, in part because they involve extensive oxidative modifications at the break termini. Prior to completion of DSB repair, the chemically modified termin...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Lonnie P. Swift, B. Christoffer Lagerholm, Lucy R. Henderson, Malitha Ratnaweera, Hannah T. Baddock, Blanka Sengerova, Sook Lee, Abimael Cruz-Migoni, Dominic Waithe, Christian Renz, Helle D. Ulrich, Joseph A. Newman, Christopher J. Schofield, Peter J. McHugh
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2024-06-01
Serija:	Nature Communications
Online dostop:	https://doi.org/10.1038/s41467-024-49583-5
Oznake:	Označite Brez oznak, prvi označite!