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SNM1A is crucial for efficient repair of complex DNA breaks in human cells

Abstract DNA double-strand breaks (DSBs), such as those produced by radiation and radiomimetics, are amongst the most toxic forms of cellular damage, in part because they involve extensive oxidative modifications at the break termini. Prior to completion of DSB repair, the chemically modified termin...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Lonnie P. Swift, B. Christoffer Lagerholm, Lucy R. Henderson, Malitha Ratnaweera, Hannah T. Baddock, Blanka Sengerova, Sook Lee, Abimael Cruz-Migoni, Dominic Waithe, Christian Renz, Helle D. Ulrich, Joseph A. Newman, Christopher J. Schofield, Peter J. McHugh
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2024-06-01
Sraith:Nature Communications
Rochtain ar líne:https://doi.org/10.1038/s41467-024-49583-5
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