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Phenotype and functionality of follicular helper T cells in patients with acute dengue infection

Abstract Background The association of functionality and phenotype of follicular helper T cells (Tfh) with dengue virus (DENV) specific antibody responses and clinical disease severity has not been well studied. Methods We investigated the phenotype and functionality of Tfh cells and plasmablasts in...

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Автори: Ayesha Wijesinghe, Jayani Gamage, Hemantha Goonewardena, Laksiri Gomes, Deshni Jayathilaka, Dulharie T. Wijeratne, Ruklanthi de Alwis, Chandima Jeewandara, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie Neelika Malavige
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2020-04-01
Серія:Journal of Biomedical Science
Предмети:
Follicular helper T cells
Plasmablasts
IL-21
Neutralizing antibodies
NS1 antibodies
Viral loads
Онлайн доступ:http://link.springer.com/article/10.1186/s12929-020-00641-2
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