Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis

<p>Abstract</p> <p>Background</p> <p>Leukotrienes are potent inflammatory mediators, which in a number of studies have been found to be associated with ischemic stroke pathology: gene variants affecting leukotriene synthesis, including the FLAP (ALOX5AP) gene, have in human studies shown correlation...

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Detalles Bibliográficos

Autores principales:	Ström Jakob O, Strid Tobias, Hammarström Sven
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2012-11-01
Colección:	BMC Neuroscience
Materias:	Brain infarction Leukotrienes Alox5ap protein FLAP Mice Middle cerebral artery occlusion
Acceso en línea:	http://www.biomedcentral.com/1471-2202/13/146
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