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ALOX5AP Predicts Poor Prognosis by Enhancing M2 Macrophages Polarization and Immunosuppression in Serous Ovarian Cancer Microenvironment

BackgroundSerous ovarian cancer (SOC) is a highly lethal gynecological malignancy with poor prognosis. Given the importance of the immune-related tumor microenvironment (TME) in ovarian cancer, investigating tumor-immune interactions and identifying novel prognostic and therapeutic targets in SOC is...

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Principais autores: Xiang Ye, Limei An, Xiangxiang Wang, Chenyi Zhang, Wenqian Huang, Chenggong Sun, Rongrong Li, Hanlin Ma, Hongyan Wang, Min Gao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-05-01
coleção:Frontiers in Oncology
Assuntos:
targeted therapy
serous ovarian cancer
ALOX5AP
immunosuppression
prognosis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2021.675104/full
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