Profiling parvalbumin interneurons using iPSC: challenges and perspectives for Autism Spectrum Disorder (ASD)

Abstract Autism spectrum disorders (ASD) are persistent conditions resulting from disrupted/altered neurodevelopment. ASD multifactorial etiology—and its numerous comorbid conditions—heightens the difficulty in identifying its underlying causes, thus obstructing the development of effective therapie...

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Autori principali:	Federica Filice, Beat Schwaller, Tanja M. Michel, Edna Grünblatt
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2020-01-01
Serie:	Molecular Autism
Soggetti:	Parvalbumin Induced pluripotent stem cells Autism spectrum disorder Schizophrenia CRISPR-Cas9 technology GABAergic
Accesso online:	https://doi.org/10.1186/s13229-020-0314-0
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