Spatial control of the APC/C ensures the rapid degradation of cyclin B1

Abstract The proper control of mitosis depends on the ubiquitin-mediated degradation of the right mitotic regulator at the right time. This is effected by the Anaphase Promoting Complex/Cyclosome (APC/C) ubiquitin ligase that is regulated by the Spindle Assembly Checkpoint (SAC). The SAC prevents th...

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Autors principals:	Luca Cirillo, Rose Young, Sapthaswaran Veerapathiran, Annalisa Roberti, Molly Martin, Azzah Abubacar, Camilla Perosa, Catherine Coates, Reyhan Muhammad, Theodoros I Roumeliotis, Jyoti S Choudhary, Claudio Alfieri, Jonathon Pines
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer Nature 2024-08-01
Col·lecció:	The EMBO Journal
Matèries:	Mitosis Cell Cycle Ubiquitin Chromosome Nucleosome
Accés en línia:	https://doi.org/10.1038/s44318-024-00194-2
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