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Spatial control of the APC/C ensures the rapid degradation of cyclin B1

Abstract The proper control of mitosis depends on the ubiquitin-mediated degradation of the right mitotic regulator at the right time. This is effected by the Anaphase Promoting Complex/Cyclosome (APC/C) ubiquitin ligase that is regulated by the Spindle Assembly Checkpoint (SAC). The SAC prevents th...

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Uloženo v:
Hlavní autoři: Luca Cirillo, Rose Young, Sapthaswaran Veerapathiran, Annalisa Roberti, Molly Martin, Azzah Abubacar, Camilla Perosa, Catherine Coates, Reyhan Muhammad, Theodoros I Roumeliotis, Jyoti S Choudhary, Claudio Alfieri, Jonathon Pines
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Nature 2024-08-01
Edice:The EMBO Journal
Témata:
Mitosis
Cell Cycle
Ubiquitin
Chromosome
Nucleosome
On-line přístup:https://doi.org/10.1038/s44318-024-00194-2
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